Name | ethyl hydrazinoacetate hydrochloride |
Synonyms | Ethyl hydrazinoacetate HCl ETHYL HYDRAZINEACETATE HCL ETHYL HYDRAZINOACETATE HCL EthylHydrzinocetateHydrochloride Ethyl hydrazinoacetate hydrochloride ethyl hydrazinoacetate hydrochloride ETHYL HYDRAZINOACETATE HYDROCHLORIDE HYDRAZINO-ACETIC ACID ETHYL ESTER HCL HYDRAZINO-ACETIC ACID ETHYL ESTER HYDROCHLORIDE Acetic acid, hydrazino-, ethyl ester, monohydrochloride |
CAS | 6945-92-2 |
EINECS | 230-104-3 |
InChI | InChI=1/C4H10N2O2.ClH/c1-2-8-4(7)3-6-5;/h6H,2-3,5H2,1H3;1H |
InChIKey | HZZRIIPYFPIKHR-UHFFFAOYSA-N |
Molecular Formula | C4H11ClN2O2 |
Molar Mass | 154.6 |
Melting Point | 152-154°C(lit.) |
Boling Point | 223°C at 760 mmHg |
Flash Point | 88.6°C |
Vapor Presure | 0.0988mmHg at 25°C |
Appearance | Solid |
Color | Clear colorless to pale yellow |
BRN | 3912112 |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
MDL | MFCD00012923 |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29280000 |
Hazard Class | IRRITANT |
Background | ethyl hydrazide hydrochloride is a very important intermediate in organic synthesis, it is a key intermediate for many nitrogen-containing heterocyclic compounds. Nitrogen Heterocycles are important structural components in many drugs. According to the drug data approved by the U. S. Food and Drug Administration (fda), 59% of the unique small molecule drugs contain nitrogen heterocyclic compounds. In recent years, more and more attention has been paid to small molecule heterocyclic drugs. And the domestic market is now circulating hydrazine ethyl acetate hydrochloride basically from Europe, the price is expensive, poor economic efficiency, to the domestic enterprises to develop new products inconvenience. |
Application | ethyl hydrazide hydrochloride is a very important intermediate in organic synthesis, it is a key intermediate of many nitrogen-containing heterocyclic compounds, mainly used in laboratory organic synthesis and chemical pharmaceutical research and development process. |
synthetic method | sodium chloroacetate was obtained by reaction of chloroacetic acid with sodium hydroxide in the presence of catalyst, the resulting intermediate is then acidified by reaction with hydrazine hydrate in the presence of sodium hydroxide and esterified to obtain ethyl hydrazinoacetate hydrochloride, the target product of the present invention. |
Use | ethyl hydrazide hydrochloride has a wide range of applications in the laboratory research and development process and chemical and pharmaceutical synthesis process. |